PRFM vs. PRP: Everything You Need to Know

If you’ve heard of Platelet-Rich Plasma (PRP) therapy, you may be familiar with its powerful regenerative effects for skin rejuvenation, hair restoration, and overall healing. But what if there was an even more advanced version that could provide longer-lasting and more effective results? Enter Platelet-Rich Fibrin Matrix (PRFM)—an evolution of PRP that utilizes the body’s natural healing properties for even better outcomes.
At Vigour Aesthetics + Wellness, a leading Albany med spa, we specialize in cutting-edge, non-surgical treatments that use your body’s own biology to restore, rejuvenate, and enhance your natural, youthful appearance. Today, we’re diving deep into PRFM treatments and answering key questions:
- How is PRFM different from PRP?
- How does PRFM compare to other types of fillers?
PRFM vs. PRP: What’s the Difference?
PRFM and PRP both utilize platelets derived from your own blood to stimulate collagen production, promote tissue regeneration, and enhance healing. However, PRFM is a more advanced version of PRP with key improvements that lead to better results. Here at Vigour Aesthetics + Wellness med spa in Albany, we use the innovative Selphyl® system for preparing PRFM.
1. PRFM has a more stable and sustained release of growth factors
PRP releases its growth factors almost immediately after being injected into the skin, which means its regenerative effects begin right away but diminish quite quickly. PRFM, on the other hand, forms a fibrin matrix—a natural (gel-like) scaffold that holds the platelets in place and releases growth factors over time. This slow, controlled release allows for extended healing and collagen stimulation.
2. PRFM typically lasts longer than PRP
Since PRFM delivers growth factors gradually over several days, the results tend to be longer-lasting than traditional PRP treatments. This means you may require fewer treatments to achieve your desired outcome, making it a more cost and time-efficient choice for skin and hair rejuvenation.
3. PRFM contains a higher concentration of platelets
PRFM is processed differently from PRP, leading to a purer and more concentrated formula. By eliminating red and white blood cells, PRFM reduces inflammation while enhancing the regenerative potential of your platelets.
4. PRFM has a gel-Like consistency for better precision
Unlike PRP, which remains in liquid form, PRFM turns into a gel-like substance that stays in place when injected. This consistency makes PRFM an ideal alternative option for facial filler, volume restoration, and scar treatment, as it can be placed exactly where it’s needed without spreading unpredictably.
PRFM vs. Traditional Fillers: How Do They Compare?
Many people interested in PRFM Albany treatments wonder how it stacks up against dermal fillers like hyaluronic acid (HA) injectables. While both can enhance facial volume and improve skin quality, there are some major differences:
1. PRFM is completely natural
Traditional fillers can contain synthetic materials like hyaluronic acid or calcium hydroxyapatite, while PRFM is 100% derived from your own blood. If you’re looking for a completely autologous (natural) treatment, PRFM is a fantastic option.
2. PRFM stimulates collagen production instead of simply adding volume
Fillers work by instantly plumping the skin to smooth wrinkles and restore lost volume. PRFM, on the other hand, stimulates your body to produce collagen and elastin, creating a gradual yet natural rejuvenation that improves skin quality over time.
3. PRFM provides longer-lasting results
Dermal fillers typically last between 6 months to 2 years, depending on the type. PRFM results can last even longer because they trigger your body’s natural healing process rather than simply adding temporary volume.
4. PRFM is less likely to cause reactions
Since PRFM is derived from your own blood, there is virtually no risk of allergic reactions or rejection. Dermal fillers, while extremely safe and effective, can sometimes cause swelling, lumps, or immune reactions in certain individuals.
5. PRFM works well with fillers for a comprehensive approach
If you want the instant plumping effects of fillers but also want long-term collagen regeneration, PRFM can be combined with traditional fillers for the best of both worlds. Many clients at our Albany med spa choose this combination for superior facial rejuvenation.
What Can PRFM Treat?
At Vigour Aesthetics + Wellness med spa in Albany, we offer PRFM treatments to help with:
✅ Facial rejuvenation – Reducing wrinkles, fine lines, and volume loss
✅ Hair restoration – Stimulating hair follicles for thicker, healthier hair
✅ Scar and acne scar improvement – Encouraging skin healing and collagen remodeling
✅ Under-eye rejuvenation – Treating hollowness, dark circles, and fine lines
✅ Skin texture and tone enhancement – Improving overall skin health and elasticity
Is PRFM Right for You?
PRFM is an excellent option if you’re looking for a natural, regenerative treatment with long-lasting results. It’s ideal for individuals seeking:
✔ A non-surgical anti-aging solution
✔ A natural alternative to traditional fillers
✔ Skin rejuvenation and hair restoration
✔ A treatment with minimal downtime and low risk
PRFM Albany: Your Path to Natural Rejuvenation
At Vigour Aesthetics + Wellness, we are committed to providing the most advanced and effective regenerative treatments to help you look and feel your best. Whether you’re interested in PRFM for facial rejuvenation, hair growth, or scar improvement, we’re here to help you achieve your aesthetic goals.
If you’re searching for the best Albany med spa offering PRFM, book your consultation today and discover the power of regenerative beauty!
Call us at (844) 844-6871 or book your consultation online